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Gd and 
Gd in the thermal energy region with the Li-glass detectors and NaI(Tl) spectrometer installed in J-PARC
MLFANNRIKimura, Atsushi; Nakamura, Shoji; Endo, Shunsuke; Rovira Leveroni, G.; Iwamoto, Osamu; Iwamoto, Nobuyuki; Harada, Hideo; Katabuchi, Tatsuya*; Terada, Kazushi*; Hori, Junichi*; et al.
Journal of Nuclear Science and Technology, 60(6), p.678 - 696, 2023/06
Times Cited Count：2 Percentile：53.91(Nuclear Science & Technology)Kojima, Kensuke
Proceedings of International Conference on the Physics of Reactors; Unifying Theory and Experiments in the 21st Century (PHYSOR 2016) (USB Flash Drive), p.3283 - 3292, 2016/05
The MOSRA system has been developing to improve the applicability of the neutronic characteristic analyses. The cell calculation module MOSRA-SRAC is a core module of MOSRA, and applicability tests for realistic problems are required. As a test, MOSRA-SRAC is validated by comparison with measured values. As the measurement, the post irradiation examination SFCOMPO 99-5 is chosen. In the examination, the compositions of major heavy metal and fission product nuclides in a UO
-GdO
fuel rod pulled from the 8
8 BWR fuel assembly used in TEPCO's Fukushima-Daini-2 were measured. The result shows good agreement between calculated and measured value. For uranium and plutonium nuclides, calculated values agree within 5% except for 
Pu. Pu composition is overestimated by 30%, and the overestimation is caused by the unclearness of the void faction history of the fuel rod. For fission products, calculated values agree within approximately 10%.
studyMatsumura, Akira*; Zhang, T.*; Nakai, Kei*; Endo, Kiyoshi*; Kumada, Hiroaki; Yamamoto, Tetsuya*; Yoshida, Fumiyo*; Sakurai, Yoshinori*; Yamamoto, Kazuyoshi; Nose, Tadao*
Journal of Experimental and Clinical Cancer Research, 24(1), p.93 - 98, 2005/03
no abstracts in English
evaluation of BPA-Gd-DTPA complex as an MRI contrast agent and as a carrier for neutron capture therapyTakahashi, Kazunori*; Nakamura, Hiroyuki*; Furumoto, Shozo*; Yamamoto, Kazuyoshi; Matsumura, Akira*; Fukuda, Hiroshi*; Yamamoto, Yoshinori*
Proceedings of 11th World Congress on Neutron Capture Therapy (ISNCT-11) (CD-ROM), 1 Pages, 2004/10
We synthesized a BPA-Gd-DTPA compound, as a carrier for neutron capture therapy to be used for MRI contrast media. Pinanediol was used as the protective group for B(OH)2 group of BPA, and the BPA unit was connected to the DTPA framework through an amide bond. The biodistribution studies were performed after injection of the compound into AH109A hepatoma bearing Donryu rats. The concentrations of Gd and boron were measured by prompt g-ray analyses. The tumor uptakes (% ID/g) were 1% and 0.3% at 20 min and 60 min after injection, respectively and were higher than that of carborane-Gd-DTPA, which we previously reported. However, liver and kidney uptake was very high and tumor/blood ratio was very low (0.38) compared to that of BPA itself (ca. 3.0). Alfa autoradiogram of a tumor bearing rat showed higher concentration of boron in the tumor compared to surrounding muscle and very high in the intestine. Although tumor selectivity of the compound was higher than that of carborane-Gd-DTPA, further studies of the synthesis and in vivo evaluation of better binary compounds are continuing.
Endo, Kiyoshi*; Shibata, Yasushi*; Yoshida, Fumiyo*; Nakai, Kei*; Yamamoto, Tetsuya*; Matsumura, Akira*; Ishii, Keizo*; Sakai, Takuro; Sato, Takahiro; Oikawa, Masakazu*; et al.
Proceedings of 11th World Congress on Neutron Capture Therapy (ISNCT-11) (CD-ROM), 2 Pages, 2004/10
Micro PIXE, which is installed in a single end accelerator in JAERI, was used for quantitative analysis of boron and gadolinium distribution in a cell level. The micro beam of 1 
m diameter is possible to observe the distribution. In the adjustment procedure of the sample, first is a fix of mylar film by using a glass ring and a bite ring of 2cm diameter. Next the 9L cells were scattered on the washed film, and is cultivated on 37
C in medium until they form the mono-layer. After the Gd-BOPTA was added, it incubates for the 24-72 hour on 37C. The film is washed in the THAM liquid, and is directly put on liquid nitrogen. A vacuum drying for 24 hours is conducted in order to fix a film on holder. It is important to uniformly fix the cell in distribution analysis in the cell using Micro PIXE. In recent result, it became possible that the distribution of P, S, Gd, etc. was analyzed. But we could not distinguish whether K and Gd exist in the cell or whether it exists around the cell. It was indicated that these elements was leaked by the reason of cell breaking or other on the cytoplasm.
NCT trialZhang, T.*; Matsumura, Akira*; Yamamoto, Tetsuya*; Yoshida, Fumiyo*; Sakurai, Yoshinori*; Kumada, Hiroaki; Yamamoto, Kazuyoshi; Nose, Tadao*
Research and Development in Neutron Capture Therapy, p.819 - 824, 2002/09
From present study, the irradiation effect by using combination of Boron and Gd, showed various irradiation effects (additive effect, less than additive effect, non additive effect), which depend on Gd concentration. The additive effect will be occurred when using a combination of Gd and Boron with low concentration, however, adding Gd to high concentration will reduce additive effect resulting in less than additive to finally non-additive effect. This result indicate that achieving suitable concentrations of Gd and Boron together in tumors may increase the therapy effect, but achieving excess concentration of Gd with Boron together in tumor may cause negative therapeuitic effect.
Fujino, Takeo*; Sato, Nobuaki*; Yamada, Kota*; Okazaki, Manabu*; Fukuda, Kosaku; Serizawa, Hiroyuki; Shiratori, Tetsuo*
Journal of Nuclear Materials, 289(3), p.270 - 280, 2001/03
Times Cited Count：2 Percentile：19.66(Materials Science, Multidisciplinary)no abstracts in English
and (U,Gd)OMinato, Kazuo; Shiratori, Tetsuo; Serizawa, Hiroyuki; Hayashi, Kimio; Une, Katsumi*; Nogita, Kazuhiro*; Hirai, Mutsumi*; Amaya, M.*
Journal of Nuclear Materials, 288(1), p.57 - 65, 2001/01
Times Cited Count：21 Percentile：80.29(Materials Science, Multidisciplinary)no abstracts in English
*; Arakawa, Takuya*; Okuno, Hiroshi
JAERI-Data/Code 94-018, 36 Pages, 1994/12
JAERI-Data-Code-94-018.pdf:1.09MB
no abstracts in English
Okuno, Hiroshi; Nomura, Yasushi
JAERI-Data/Code 94-014, 33 Pages, 1994/10
JAERI-Data-Code-94-014.pdf:0.98MB
no abstracts in English
Ogura, Koichi; Shibata, Takemasa
Journal of the Physical Society of Japan, 63(3), p.834 - 838, 1994/03
Times Cited Count：2 Percentile：46.01(Physics, Multidisciplinary)no abstracts in English
Nishimura, Akihiko; Arisawa, Takashi; Oba, Hironori; Shibata, Takemasa
J. Vac. Sci. Technol., A, 11(4), p.1516 - 1521, 1993/07
no abstracts in English
Nishimura, Akihiko; Oba, Hironori; Shibata, Takemasa
Journal of Nuclear Science and Technology, 29(11), p.1054 - 1060, 1992/11
no abstracts in English
solid solutions; ; ;
Journal of Nuclear Materials, 105(2), p.201 - 210, 1982/00
Times Cited Count：82 Percentile：98.6(Materials Science, Multidisciplinary)no abstracts in English
;
Journal of Radioanalytical Chemistry, 45, p.155 - 167, 1978/00
no abstracts in English
) Reaction:Purity of 
Tb Product and Yields Radioisotopes in an Intense Neutron Absorption Material,GdO;
JAERI-M 6668, 45 Pages, 1976/08
no abstracts in English
